Most cancers of the prostate are classified as:

Prostate cancers are predominantly classified as adenocarcinomas because they originate from glandular epithelial cells in the prostate gland. This type of cancer typically forms in the areas of the prostate that produce fluid, contributing to seminal fluid. Adenocarcinomas account for more than 95% of all prostate cancer cases, making them the most common form by far.

The structure and function of the prostate are closely tied to glandular tissues, and tumors arising from these cells are characterized by specific histological features typical of adenocarcinomas, such as gland formation and mucin production. Understanding this classification is crucial for diagnosis and treatment, as adenocarcinomas have distinct biological behaviors and responses to therapies compared to other types of tumors.

In contrast, sarcomas, myelomas, and squamous cell carcinomas are either rare in the context of prostate cancer or arise from different types of tissues and cell types. Sarcomas originate from connective tissues, myelomas are cancers of plasma cells found in the bone marrow, and squamous cell carcinomas arise from squamous cells, typically found in surfaces of various organs. Thus, recognizing adenocarcinoma as the prevalent type of prostate cancer allows for a focused approach in clinical