Organelle that contains the code needed for oxidative phosphorylation is:

The organelle that contains the code needed for oxidative phosphorylation is the mitochondria. This is primarily because mitochondria are well-known as the powerhouse of the cell, where adenosine triphosphate (ATP) is produced through the process of oxidative phosphorylation. The mitochondria contain their own DNA, which encodes essential proteins required for the electron transport chain and ATP synthesis.

During oxidative phosphorylation, electrons are transferred through a series of protein complexes located in the inner mitochondrial membrane. This transfer of electrons creates a proton gradient that drives ATP production via ATP synthase. The enzymes and proteins critical for this process are indeed encoded by mitochondrial DNA, underlining the role of mitochondria not only in energy production but also as sites of genetic information crucial for this metabolic pathway.

Other organelles listed do not partake in oxidative phosphorylation. Lysosomes are involved in waste processing and cellular digestion, while the nucleus serves as the control center of the cell, housing genetic material and regulating gene expression, but does not directly engage in energy production through oxidative phosphorylation. Vacuoles primarily function in storage and transport, playing no role in the metabolic processes of ATP generation.